Levamisole hydrochloride CAS 16595-80-5 Product Information

Synonyms

How to Store Levamisole hydrochloride CAS 16595-80-5

Levamisole hydrochloride CAS 16595-80-5 applications

1. Chemical Structure: Levamisole hydrochloride has a chemical formula of C11H12N2S·HCl. It is the hydrochloride salt of levamisole, which is a synthetic compound.
2. Medical Uses: Levamisole hydrochloride is used in both veterinary and human medicine. In veterinary medicine, it is primarily used as an anthelmintic to treat and control parasitic infections in animals, including roundworms and hookworms. In humans, it has been used as an immunomodulatory agent and has also shown antiparasitic activity against certain worms.
3. Mode of Action: Levamisole hydrochloride works by stimulating the immune system and affecting the neurotransmitters of the parasites, leading to paralysis and death of the worms. It is believed to enhance the immune response against parasites.
4. Veterinary Applications: Levamisole hydrochloride is commonly used in livestock, such as cattle, sheep, and pigs, to treat gastrointestinal nematode infections. It may also be used in horses and dogs in certain cases. It is usually administered orally or via injection, with dosages and treatment regimens determined by a veterinarian.
5. Human Applications: Levamisole hydrochloride was previously used in humans as an immunomodulatory agent, particularly in the treatment of certain autoimmune diseases and as an adjuvant in cancer therapy. However, its use in human medicine has been largely discontinued due to adverse effects and safety concerns.
6. Safety Considerations: Levamisole hydrochloride may cause adverse effects in animals and humans. In animals, potential side effects include gastrointestinal disturbances, hypersensitivity reactions, and rare cases of agranulocytosis (a decrease in white blood cells). In humans, levamisole has been associated with severe adverse effects, including agranulocytosis and vasculitis. It is important to use levamisole hydrochloride strictly according to the prescribed guidelines and under the supervision of a veterinarian or healthcare professional.
7. Availability: Levamisole hydrochloride is a controlled substance and its availability may be regulated by local regulations and veterinary prescription requirements. It is typically obtained through veterinary pharmaceutical suppliers or manufacturers.